Kris Huygen Selected Research

AG 85

1/2014	The Immunodominant T-Cell Epitopes of the Mycolyl-Transferases of the Antigen 85 Complex of M. tuberculosis.
1/2011	T cell reactivity against mycolyl transferase antigen 85 of M. tuberculosis in HIV-TB coinfected subjects and in AIDS patients suffering from tuberculosis and nontuberculous mycobacterial infections.
1/2006	Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle.
7/2003	Gamma interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-mycobacterium bovis BCG-vaccinated Malawian young adults.

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Kris Huygen Research Topics

Disease

36	Tuberculosis (Tuberculoses) 11/2016 - 04/2002
27	Infections 09/2021 - 04/2002
10	Paratuberculosis (Johne's Disease) 07/2017 - 01/2006
7	Whooping Cough (Pertussis) 10/2017 - 08/2015
6	Buruli Ulcer 01/2018 - 05/2007
5	Tetanus 10/2017 - 08/2015
5	Diphtheria 10/2017 - 08/2015
3	Latent Tuberculosis 03/2015 - 04/2003
3	Inflammation (Inflammations) 04/2013 - 10/2007
3	Bovine Tuberculosis 08/2008 - 04/2002
3	Hypoxia (Hypoxemia) 01/2008 - 02/2007
2	Asthma (Bronchial Asthma) 01/2018 - 03/2012
2	Neoplasms (Cancer) 11/2016 - 08/2007
2	Pulmonary Tuberculosis 03/2014 - 11/2004
2	Necrosis 10/2013 - 04/2003
2	Latent Infection 03/2010 - 02/2007
2	Fowlpox 01/2005 - 07/2004
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 11/2016
1	Communicable Diseases (Infectious Diseases) 08/2015
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 04/2014
1	Immune System Diseases (Immune Disorders) 10/2013
1	Pneumonia (Pneumonitis) 04/2013
1	Allergic Rhinitis 03/2012
1	Emerging Communicable Diseases (Emerging Infectious Diseases) 01/2012
1	HIV Infections (HIV Infection) 01/2011
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2011
1	Acute Disease 03/2010
1	Coinfection 03/2010
1	Toxoplasmosis 03/2010
1	Lung Diseases (Lung Disease) 10/2007
1	Fibrosis (Cirrhosis) 10/2007

Drug/Important Bio-Agent (IBA)

31	VaccinesIBA 10/2017 - 04/2003
20	AntigensIBA 01/2018 - 04/2002
13	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 04/2002
10	DNA VaccinesIBA 12/2014 - 04/2002
9	AntibodiesIBA 10/2017 - 08/2008
9	Proteins (Proteins, Gene)FDA Link 11/2015 - 04/2002
7	BCG Vaccine FDA Link 01/2008 - 11/2004
6	Immunoglobulin G (IgG)IBA 09/2021 - 08/2015
5	Tuberculin (PPD)IBA 02/2018 - 04/2002
4	LipidsIBA 01/2018 - 01/2008
4	Pertussis ToxinIBA 04/2016 - 10/2015
4	AG 85IBA 01/2014 - 07/2003
4	CytokinesIBA 10/2013 - 05/2005
4	TransferasesIBA 01/2011 - 07/2004
3	mycolactoneIBA 01/2018 - 01/2012
3	Subunit VaccinesIBA 11/2016 - 11/2004
3	MVA 85AIBA 03/2015 - 07/2004
3	AerosolsIBA 06/2012 - 04/2003
2	Peptides (Polypeptides)IBA 02/2018 - 01/2003
2	EnzymesIBA 01/2018 - 01/2008
2	Polyketide SynthasesIBA 01/2018 - 01/2014
2	Immunoglobulin E (IgE)IBA 01/2018 - 04/2013
2	Interferon-gamma (Interferon, gamma)IBA 07/2017 - 01/2006
2	Pertussis VaccineIBA 01/2016 - 01/2016
2	pertactin FDA Link 01/2016 - 01/2016
2	Interleukin-10 (Interleukin 10)IBA 10/2013 - 03/2008
2	Interleukin-6 (Interleukin 6)IBA 10/2013 - 03/2008
2	Interleukin-17 (Interleukin 17)IBA 10/2013 - 03/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2007 - 02/2007
2	Phosphates (Orthophosphate)IBA 07/2006 - 03/2005
1	Interleukin-5 (Interleukin 5)IBA 01/2018
1	Acyl Carrier ProteinIBA 01/2018
1	Acetates (Acetic Acid Esters)FDA Link 01/2018
1	AcyltransferasesIBA 01/2018
1	Diphtheria-Tetanus-acellular Pertussis Vaccines (Tripedia)FDA Link 10/2017
1	Pathogen-Associated Molecular Pattern MoleculesIBA 11/2016
1	BoostrixIBA 01/2016
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 01/2016
1	Combined VaccinesIBA 01/2016
1	Isoniazid (Ftivazide)FDA LinkGeneric 03/2015
1	Tuberculosis VaccinesIBA 01/2015
1	Therapeutic UsesIBA 04/2014
1	InterferonsIBA 10/2013
1	Immunodominant EpitopesIBA 09/2013
1	Peptide Hydrolases (Proteases)FDA Link 04/2013
1	Biomarkers (Surrogate Marker)IBA 12/2012
1	TrehaloseIBA 06/2012
1	Cord FactorsIBA 06/2012
1	cyclopropaneIBA 06/2012
1	Monoclonal AntibodiesIBA 03/2012
1	ExotoxinsIBA 01/2012
1	Interleukin-23 (Interleukin 23)IBA 01/2011
1	Interleukin-12 (IL 12)IBA 01/2011
1	AutovaccinesIBA 01/2011
1	Protein Isoforms (Isoforms)IBA 06/2009
1	Liver X ReceptorsIBA 06/2009
1	1- phenyl- 6,7- dimethoxy- 1,2,3,4- tetrahydroisoquinoline (S-23)IBA 05/2008
1	CaspasesIBA 03/2008
1	Caspase 3 (Caspase-3)IBA 03/2008
1	Isocitrate LyaseIBA 01/2008
1	Fibronectins (Fibronectin)IBA 10/2007
1	Hydroxyproline (4 Hydroxyproline)IBA 10/2007
1	AllergensIBA 10/2007
1	LigandsIBA 08/2007
1	LectinsIBA 08/2007
1	Histocompatibility Antigens Class IIBA 08/2007
1	Toll-Like Receptors (Toll-Like Receptor)IBA 07/2007

Therapy/Procedure

2	Therapeutics 03/2015 - 06/2009
1	Intranasal Administration 10/2007